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Causes of Chronic Kidney Disease (CKD) in Children

Provided by Expert Zhang Youkang on 2013-10-17 15:01

Causes of Chronic Kidney Disease (CKD) in ChildrenKidneys are a pair of vital organs in our body. One of important functions is to remove waste products from body.The kidneys also regulate blood pressure,balance chemical levels and secrete some kinds of hormones. Chronic kidney disease (CKD) can affect the children' development and growth significantly.If left uncontrolled,the children will have to live with dialysis or kidney transplant. What are the causes of CKD in children?

The conditions and diseases that lead to CKD in children can not be fixed easily. Often, the condition will develop so slowly that it goes unnoticed untile the kidneys have been permanently damaged. The below is a list of possible causes of CKD in children.

Systemic disorders

Systemic disorders can affect many parts of the body including kidneys in some cases. Diabetes and lupus are two common systemic disorders which can involve kidneys. In lupus, the immune system attacks the body cells and tissues by mistake, resulting in inflammation in kidneys.Diabetes is the leading cause of Kidney Failure in adults, but it is not a common cause of CKD in children.This is because it usually takes years for diabetes to cause kidney problem.

Hereditary diseases

Polycystic kidney disease(PKD) is the most common genetic kidney disease, in which numerous cysts develop in both of kidneys. The cysts keep enlarging and replace more and more healthy kidney tissues. Over time, CKD occurs. In Alport Syndrome, the defective gene that causes kidney disease may also cause hearing loss or vision loss.


Glomerulonephritis is featured with inflammation of filters in kidneys. post-streptococcal glomerulonephritis is commonly seen in children. Protein in urine is a typical sign of glomerulonephritis.

Blocked urine flow and reflux

If blockage develops between the kidneys and the opening where urine leaves the body, the urine can back up and damage the kidneys. Over time, renal function will decline.

The above are the possible causes of CKD in children. If the causes in your child’s case have not be confirmed, you can email to kidneyabc@hotmail.com  and we can help analyze the overall condition and then give a reply.

If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.

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