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What are the causes of chronic allograft nephropathy? It is a mostly concerned issue for people who have kidney transplant. This article will give you an explanation.
With improved immunosuppressive and early allograft survival, chronic allograft nephropathy has become the dominant cause of kidney transplant failure.It is featured with progressive loss of renal function.Clinically,it presents with hypertension and proteinuria. A rise in the serum creatinine level is the most sensitive and reliable indicator of possible rejection and may may be only sign.
There are numerous risk factors for graft injury have been identified as possible contributors to chronic allograft nephropathy.
Acute injury:donor factors, vascular obstruction, drug toxicity, infection, recurrent disease and delayed graft function.
Chronic injury: long-term use of immunosuppressive drugs, poorly controlled blood pressure,dyslipidemia,DM.
The above are the possible causes of chronic allograft nephropathy. If the controllable risk factors can be avoided, the incidence of chronic allograft nephropathy will reduce significantly.
What is the treatment for Chronic Allograft Nephropathy?
Treating the above conditions effectively can reduce damage to the new kidney.However,once the transplanted kidney fails to work,the patients have to return to Dialysis or receive another Kidney Transplant.The life on dialysis is really hard.Also,the incidence of failure of the transplanted kidney may be higher after second transplant.
In consideration of these problems,an alternative treatment is recommended to people with chronic allograft nephropathy called Micro-Chinese Medicine Osmotherapy.
Micro-Chinese Medicine Osmotherapy is a natural therapy based on traditional Chinese medicine. Based on the patients’ specific condition, a variety of Chinese medicines are applied in it. As it is a plant based therapy, it has no invasive effects on kidneys. This therapy not only can help control the risk factors of chronic allograft nephropathy to stop renal function decline, but also can restore the impaired kidney structure and enhance renal function. So there will not be need for dialysis and kidney transplant.