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Can High Blood Pressure Lead to End-Stage Renal Disease

2012-09-28 08:59

Can High Blood Pressure Lead to End-Stage Renal DiseaseHigh blood pressure, or hypertension, is characterized by the increase of arterial pressure level. It is closely associated with End-Stage Renal Disease. If the hypertension is not well controlled, End-Stage Renal Disease can be caused.

Persistent high blood pressure can result in kidney damage directly, which is known as Hypertensive Nephropathy. In the early stage, this disease generally causes no symptoms, and affected person may experience increased urine at night and slight protein in the urine. If Hypertensive Nephropathy progresses to the final stage, End-Stage Renal Disease occur. Study shows that 15% of people with hypertension may develop Uremia.

There are two types of Hypertensive Nephropathy: benign nephrosclerosis and malignant nephroslcerosis. The former is most present in people over 60 years old and it seldom result to Kidney Failure. The latter only occurs in a case of hypertension with diastolic blood pressure exceeding 130mmHg. In this condition, there may be blood and protein in the urine in the beginning and, over time, kidney function will deteriorate. Eventually, Kidney Failure can be caused.

In addition, the rate of kidney damage associated with high blood pressure is positive correlation with the severity and duration of hypertension. Other possible related factors also include smoking, alcoholism, gender, race, Diabetes, hyperlipidemia, hyperuricemia, etc. The interaction of these factors will aggravate the damage.

People with renal insufficiency often experience elevated blood pressure level, known as Renal Nephropathy. In turn, the increased blood pressure will cause kidney damage, resulting in progressive deterioration of kidney function. This vicious circle is an important factor which causes End-Stage Renal Disease in hypertensive kidney disease. Therefore, in order to avoid and delay the occurrence of renal insufficiency, patients with high blood pressure should have a good management of their blood pressure levels.

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