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Causes and Symptoms of FSGS


2013-10-09 17:43

Causes and Symptoms of FSGSFSGS is the common primary cause of Nephrotic Syndrome in both children and adults. Characterized by scarring in glomeruli, most patients have many symptoms. Finding out the causes and well management of symptoms can help treat FSGS correctly.

Causes of FSGS

According to different causes, FSGS is classified as either primary or secondary FSGS. Primary FSGS usually results from autoimmune disorders. The changes of humoral immunity and cellular immunity can cause damage to capillary walls so that large molecular protein accumulates in body. The immunoglobulin combing with C1q and C3 can cause the formation of immune complexes so as to attack kidney inherent cells. When scarring appears in glomeruli, tiny kidney filters, it indicates the onset of FSGS.

Some symptoms can remind us of FSGS

Because FSGS mainly affects the normal function of glomeruli, FSGS symptoms are usually related to damaged glomeruli. If you have FSGS, you may suffer from the following symptoms:

● Swelling: Some FSGS patients find swelling of their eyelids in the morning or swelling in legs, ankles, feet and other regions, because of fluid and sodium retention.

● Proteinuria: If there is foam in your urine persistently, it is more likely to indicate protein in urine, also known as proteinuria.

● Hematuria: When glomeruli are damaged severely, it can’t play its barrier function normally. In this case, many red blood cells leak from the kidney to form hematuria.

● High blood pressure: It isn’t as common as the above symptoms. With the progression of FSGS, patients may suffer from the increase of blood pressure. What’s worse, hypertension may reveal bad prognosis.

If you have been diagnosed with FSGS or you have one or more the above symptoms, email to kidneyabc@hotmail.com, so doctors here can help you analyze your illness condition and give some advices.



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