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Glomerulonephritis in RA is secondary to rheumatoid arthritis which is an autoimmune disorder. Routine tests can only reveal the kidney damage, but are not enough give accurate guidance to clinical treatment. That is why the disease can not be controlled effectively. Some special tests and exams are performed to diagnose glomerulonephritis in RA.
RA is an autoimmune disorder, in which there exists autoantibodies in serum. These autoantibodies can attack the kidney tissues and cells mistakenly. Autoantibody tests can reveal the types and levels of different autoantibodies in serum and tell the severity of the disease.
Circulating immune complexes tests
As for glomerulonephritis in RA, various kinds of immune complexes exist in blood. They can flow into kidneys and then cause inflammatory response in glomeruli. Circulating immune complexes tests can help find the types and amount of immune complexes. The medical results can provide accurate guidance for clinical treatment.
Lymphocyte subpopulation tests
Immune system involves the incidence of glomerulonephritis in RA. Lymphocyte subpopulation tests play an important role in monitoring the patients’ cellular immunity and humoral immunity. The tests result can provide reference for the use of drugs, especially the types and dosage of immunosuppressive drugs. Also, they can tell if the currently used treatment is effective.
Kidney damage tests
Not all people with RA will develop glomerulonephritis. Kidney damage tests can tell whether your kidneys are injured and which part of your kidneys are damage such as glomeruli or renal tubules. Also, the test results can reveal the how server your kidney damage is.
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