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Immunotherapy for Glomerulonephritis in Rheumatoid Arthritis(RA)

Provided by Expert Zhang Youkang on 2012-09-27 17:41

Rheumatoid arthritis(RA) is an autoimmune disorder and it can affect multiple body organs and systems. When kidneys are involved, it may cause glomerulonephritis. Immunotheray is an alternative treatment for the patients.

Many people may not know what autoimmune disorder is. Here is a brief introduction about it.

Immune system is a powerful protective system in our body and it can defeat the foreign harmful substances when they invade into body. However, in some cases, your immune system does not work normally and can not tell the difference between outside harmful substances from healthy body tissues and cells in your body and attacks them mistakenly.

In rheumatoid arthritis, the antibodies produced by immune system can deposit in different body parts or they may combine with antigens to form immune complexes and then lodge in different body parts.

When the antibodies and immune complexes despite in kidneys, it will cause inflammation of glomeruli which are filters in kidneys. As a result, glomerulonephritis occurs in RA.

Immunosuppressive drugs are commonly used to treat glomerulonephritis in RA. They are effective in suppressing inflammation and relieving symptoms like proteinuria. However, you may notice that it is very like to relapse. That is because the drugs only suppress the inflammation temporarily, but not regulate immune system at all.

Immunotherapy has been used to treat various kinds of refractory diseases. Up to now, it has been applied to treat immune kidney diseases successfully. It treats glomerulonephritis in RA by correcting immune dysfunction and restoring the impaired glomerular structure.

At present, the types of immunotherapy being used for treating kidney disease mainly include immunosuppressive drugs, Micro-Chinese Medicine Osmotherapy, blood purification, medicated bath.

These therapies can work together to correct immune dysfunction and restore impaired glomeruli so as to treat glomerulonephritis in RA completely.

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