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Is Kidney Biopsy a Must for Diagnosing HBV-related Nephropathy


2012-09-19 10:09

HBV-related Nephropathy refers to the kidney malfunction caused by HBV liver disease. Without an early diagnosis, the treatment can be greatly affected. Then, is kidney biopsy a must for diagnosing HBV-related Nephropathy?

Kidney biopsy

A biopsy is a conventional test used to detect the exact damaged part of kidneys so as to provide more accurate date for making a better treatment plan. It refers to the removal of a small piece of kidney tissue by a needle. This would injure the kidneys and arouse inflammation or hematuria.

The sample taken from the kidneys is regarded as hard evidence of the exact condition of the kidneys. This procedure has been applied for years, and many cases have manifested that the information provided by a biopsy only can be unilateral, which fails to judge the kidney damage.

For instance, for some people with hepatitis B, the kidney biopsy may show that most of glomeruli are unhealthy or have been dead, but, actually, their real conditions are not bad. Therefore, sometimes, the result of biopsy will mislead the treatment.

In order to make an accurate diagnosis of HBV-related Nephropathy, several special tests as below are necessary.

▪ Kidney Damage Tests

This help to figure out whether your kidneys are damaged and the kidney damage degree. Also, it can evaluate if you are sensitive to medicines.

The tests mainly include U-TP, U-malb, U-TRF, U-IGG, β2-M, α1-M etc.

▪ Toxins in Blood Tests

The tests aim to figuring out the type and amount of toxins in blood mainly including BUN, CR, UA, BMG, CycC, RBP, HCY, IL-6, PTH etc.

The test results can guide your doctor to find a right treatment option.

▪ HBV-DNA

If the tests turn positive, it tells the HBV duplication and infection.

These special tests can provide information to check the kidney condition of hepatitis B patients. Early and accurate diagnosis can help reduce kidney damage and improve the prognosis of HBV-related Nephropathy remarkably.



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