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Diagnosis for IgA Nephropathy


2012-10-18 16:49

IgA nephropathy is an autoimmune disease. The routine tests only can reflect the degree of kidney damage, but can not tell the condition of immunity and other problems. Here some special tests are recommended to the patients with IgA nephropathy.

Hematuria position diagnosis

The clinical significance of hematuria position in diagnosing IgA nephropathy is as follows:

* Reveal the red blood cells in urine are from glomeruli or urinary tract.

* Tell the severity of hematuria.

* Provide guidance for clinical treatment and clinical medications.

Kidney damage tests

Kidney damage tests mainly include the tests for urinary total protein, urinary microalbumin, U-IgG, urinary osmotic pressure, etc. These tests aim at:

* Tell whether the patients’ kidneys are damaged or not.

* Reveal which part of the kidneys is damaged, glomeruli or renal tubule.

* Degree of kidney damage and make guidance for clinical medication.

* Evaluate whether the patients with IgA Nephropathy are sensitive to the medications they are taking.

Toxins in blood tests

As kidneys are damaged in IgA nephropathy, a large amount of toxins will build up in body. Toxins in blood tests have the following functions:

* Reveal the levels and types of different toxins in blood.

* Provide guidance for choosing the right blood purification methods including dialysis, blood perfusion, plasma exchange, etc.

Complement in blood serum tests

Complement in blood plays an important role in immune system. Complement in blood serum tests are performed to determine whether deficiencies or abnormalities in the complement system are attributing to IgA nephropathy.

- If C3, C4, CH50 levels fall down, it indicates the classical pathway is activated.

- If C3B factors decline, it indicates the alternative pathway is activated.

Lymphocyte subpopulation tests

Lymphocyte subpopulation tests are important index in reflecting the immunity of the body. The test result can provide crucial reference for choosing the types and dosages of immunosuppressive drugs.

The above are the major diagnosis items in IgA nephropathy. It you are not familiar with them, you can email to kidneyabc@hotmail.com.



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