Diabetes is hard to manage. You can get a comprehensive understanding of the disease here and get the information about the latest treatments and get professional advices. read more

Micro-Chinese Medicine Osmotherapy is a brand-new therapy based on traditional Chinese herbal medicines dating back thousands of years ago. It combines the essences of herbal medicines read more

Hormonal therapy is commonly used to treat Kidney Disease in clinic. It refers to use one or more than one hormone medicines to suppress the over-reactive immune reaction read more

Patients are suggested to treat kidney disease first before they get pregnant read more

If you are diagnosed with Kidney Disease, you should talk to your doctor about starting an exercise read more

Foods and Drinks play an important role in Kidney Disease patients read more

Kidney Disease News and Events read more

In every week, a famous experienced renal medicine specialist will be invited to help diagnose and evaluate inpatient's disease condition, offering detailed therapeutic schedule. read more

Word Kidney Day Font Size A A A

Stage 4 Lupus Nephritis Prognosis

Provided by Expert Zhang Youkang on 2013-07-03 15:14

Lupus nephritis refers to inflammation of the kidney caused by systemic lupus erythematosus (SLE),a disease of the immune system.In histology, lupus nephritis can be divided into six stages.How is stage 4 lupus nephritis prognosis?

Stage 4 lupus nephritis is also called diffuse proliferative lupus nephritis. It is both the most severe, and most common subtype. In this stage, more than 50% of glomeruli are involved.The kidney lesions can be segmental or global, active or chronic. In clinic, hematuria and proteinuria are present, frequently with Nephrotic Syndrome. Also, creatinine level starts to elevate.

The prognosis of stage 4 Lupus Nephritis is poor. The patients are at definite risk of loss of kidney function.

The following risk factors can worsen the prognosis of stage 4 lupus nephritis significantly.


As stage 4 lupus nephritis is featured by diffuse proliferative lesion in kidneys,a large amount of proteins can leak into urine.Heavy protein in urine is a dangerous factor in worsening the prognosis.

High blood pressure

High blood pressure can increase renal blood flow,which can cause extra strain on kidneys.Controlling blood pressure at target level 130/80mmHg can slow the disease progression.

How to improve prognosis of stage 4 lupus nephritis?

Of course, treatment plays the key role in affecting the prognosis of stage 4 lupus nephritis.There are too forms of drug therapy for lupus nephritis” corticosteroids to control inflammation,and cytotoxic or immunosuppressive drugs to suppress the activity of immune system. However, long-term use of these drugs can cause a number of side effects such as puffy face, increased appetite, cataracts, Diabetes and infection.

Additionally,these drugs alone can not prevent the relapse of the disease. Frequent relapses can worsen the prognosis of stage 4 lupus nephritis significantly.

To improve the prognosis of stage 4 lupus nephritis, an effective treatment is required.Immunotherapy is an alternative treatment for lupus nephritis. It can treat the disease by rebuilding normal immune system and improving renal function. Thus, it can improve the prognosis of lupus nephritis fundamentally.

If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.

What else you want to know:
Make An Appointment Beijing Tongshantang Hospital of Traditional Chinese Medicine.
How can I get this treatment?
How can I get this treatment in my countries?
How much does this treatment cost?
What is the duration if I receive this treatment in your hospital?
What should I prepare to your hospital except visa?
How can I go to your hospital?

(+area code)Phone Number:
Whatsapp :
Disease Description:
contact us
patient story

Patient Story

Latest Articles