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Membranous Lupus Nephritis:Prognosis And Treatment

Provided by Expert Zhang Youkang on 2013-07-18 15:44

Lupus nephritis is secondary to systemic lupus erythematosus (SLE). In histology, it can be divided into six classes. Class Ⅴ of lupus nephritis is known as membranous lupus nephritis.What is the prognosis and treatment of membranous lupus nephritis?

Prognosis of membranous Lupus Nephritis

Membranous lupus nephritis has a segmental or a diffuse endocapillary

proliferation and it has the worst natural history.But the prognosis of membranous lupus nephritis has been improved with immunosuppressive treatment.Apart from the treatment, there is a variety of factors which can affect the prognosis mainly including

*Proteinuria:If protein in urine is above 1g/d,it is associated with a poor prognosis.

*High blood pressure: High blood pressure can make more blood flow through kidneys, which can cause extra strain on kidneys.

*Frequent relapses of SLE

*Pregnancy can worsen prognosis of membranous lupus nephritis

To determine the prognosis of membranous lupus nephritis, a variety of factors should be taken into consideration.Email to kidneyabc@hotmail.com to get an evaluation of your condition.

Treatment of membranous lupus nephritis

Corticosteroids and immunosuppressive drugs are commonly used to treat Lupus Nephritis.Corticosteroids are strong anti-inflammatory drugs and can decrease inflammation in kidneys. Immunosuppressive drugs can suppress immune system activity that damages the kidneys. Additionally, some other medicines for high blood pressure and hyperlipemia are also used to control the associated complications.

The general treatments can slow the disease progression and control some related complications and symptoms, thus improving the prognosis of membranous lupus nephritis.However,they can not stop the disease progression and the disease still can progress into Kidney Failure in some cases.

Immunotherapy is a recommended treatment for membranous lupus nephritis.It not only can control the underlying cause of lupus nephritis, immune disorder, but also can stimulate the self-regeneration of impaired kidney tissues to enhance renal function. In this way, the patients will avoid developing kidney failure completely.  Chat with our live doctor for free to learn more about this therapy.

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