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Lupus Nephritis Grade 3 with Swelling in Lower Legs

Provided by Expert Zhang Youkang on 2017-10-10 16:27

Lupus Nephritis Grade 3 with Swelling in Lower Legs,Micro-Chinese Medicine Osmotherapy“I have Lupus Nephritis grade 3...Currently taking prednisone and prednisolone... I have noticed Swelling in my lower legs.. Do I need to change medication or increase dose?”

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Lupus Nephritis: Causes and Symptoms

Causes of Lupus Nephritis

In general, lupus nephritis is a result of inflammation in the kidneys that is associated with an overactive immune (defense) system. As a consequence, antibodies against the patient’s own tissues (auto-antibodies) form antibody-tissue (antibody-antigen) unions (complexes) that in turn deposit in the kidney and initiate a destructive inflammatory reaction.

Symptoms of Lupus Nephritis

Lupus Nephritis is a serious problem. Its symptoms, though, are not always dramatic. For many, the first noticeable symptom is Swelling of the legs, ankles and feet. Less often, there can be swelling in the face or hands.

Other symptoms can vary from person to person and from day to day. They may include: Weight gain; High blood pressure; Dark urine; Foamy, frothy urine.

Treatment of Lupus Nephritis with Swelling in lower legs

Accordingly, treatment usually involves medications that reduce inflammation and suppress the immune system. When Lupus Nephritis leads to Kidney Failure, however, Dialysis or transplantation is necessary to sustain life.

* Corticosteroids (such as prednisone and prednisolone), strong anti-inflammatory drugs, can decrease kidney inflammation. But these drugs can cause a variety of potentially serious side effects, they must be monitored carefully. And you should generally taper down the dosage once the symptoms start to improve under the guidance of doctor.

* Immunosuppressive drugs, which are related to the ones used to treat cancer or prevent the rejection of transplanted organs, work by suppressing immune system activity that damages the kidneys, such as cyclophosphamide (Cytoxan), azathioprine (Imuran) and mycophenolate (Cellcept).

* Micro-Chinese Medicine Osmotherapy and other Traditional Chinese Medicine treatments

These Chinese medicine treatments can help you repair your damaged kidney tissues, prevent them from further damage in case it develops into kidney failure and restore your renal function effectively. In this way, swelling in legs can disappear naturally and you can gradually taper down the dosage and finally stop.

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