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What Is the Prognosis of Membranous Nephropathy


2013-03-05 16:13

Membranous nephropathy is a slowly progressive disorder and it mainly affects people between ages 30~50. It is a common cause of Nephrotic Syndrome in clinic. What is the prognosis of membranous nephropathy? It is affected by several factors.

Membranous Nephropathy is an immunologically medicated disease in which immune complexes deposit in the subepithelial space. The immune complexes can initiate the abnormal response of immune system, leading to inflammation in kidneys.Inflammation in kidneys can cause progressive kidney damage in the disease.

The prognosis of membranous nephropathy varies from case to case. In approximately 25% cases, the disease can remit spontaneously. About half of the patients develop microscopic hematuria. About 17% to 50% adults patients have high blood pressure from onset of membranous nephropathy. The degree and duration of proteinuria also can affect the prognosis of membranous nephropathy significantly.Controlling proteinuria less than 1g/d can improve the outcome of the disease effectively.

How to improve the prognosis of membranous nephropathy?

* Controlling high blood pressure and proteinuria plays a vital role in improving the prognosis of membranous nephropathy. Controlling proteinuria less than 1g/d and blood pressure within 125/75 mmHg can improve the disease outcome.

* Diet is an important part of membranous nephropathy treatment. A general diet for the patients should be low in salt and proteins. A dietitian can help make out a personalized dietary regime based on the patients’ condition.

*Treatment is the decisive factor in affecting the progression of Membranous Nephropathy. Immunotherapy is the best treatment option for the disease. It aims at treating the disease from its causes to stop the disease progression.

Membranous nephropathy is a progressive kidney disorder. Early treatment is adopted, better prognosis it will have.




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