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Membranous Nephropathy Complications

Provided by Expert Zhang Youkang on 2013-03-06 16:15

Membranous nephropathy is a disorder in which the filters, called glomeruli are inflamed and thickened. While some patients can have a spontaneous remission, most of the patients ultimately Kidney Failure. Membranous nephropathy complications can accelerate the deterioration of renal function.

Nephrotic syndrome

Membranous Nephropathy is the second commonest cause of Nephrotic syndrome after FSGS. Nephrotic syndrome is a group of signs and symptoms that may accompany condition that affect the filtering ability of the glomeruli. It is characterized by high protein levels in the urine, low protein levels in the blood, high blood cholesterol, and swelling.


Proteins are antibodies in blood. Loss of proteins in urine can lower immunity, thus making the patients at increased risk of infections. Also, long term use of steroids can weak the immunity. Additionally, as proteins are major nutrients in body, loss of proteins can lead to malnutrition.

High blood pressure

High blood pressure is one of common membranous nephropathy complications. The buildup of wastes in your bloodstream and salt retention can raise the blood pressure.

Thrombus and embolism

Compared to patients with other types of kidney diseases, the patients with membranous nephropathy more tend to develop thrombus and embolism. Loss of protein from the blood into the urine includes loss of proteins that help prevent clotting. So the patients are prone to develop thrombus and embolism.

Chronic renal failure

Chronic renal failure is one of serious membranous nephropathy complications. The kidneys may gradually lose their function over time to the point where the patients may require Dialysis or kidney transplant.

Acute renal failure

In some serious cases of membranous nephropathy, wastes may accumulate in blood quickly, leading to acute renal failure. If so, dialysis has to be used to remove the wastes from body.

The above is a list of membranous nephropathy complications. As these conditions can worsen renal function significantly, it is important to control them effectively early.

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