Diabetes is hard to manage. You can get a comprehensive understanding of the disease here and get the information about the latest treatments and get professional advices. read more
Micro-Chinese Medicine Osmotherapy is a brand-new therapy based on traditional Chinese herbal medicines dating back thousands of years ago. It combines the essences of herbal medicines read more
Hormonal therapy is commonly used to treat Kidney Disease in clinic. It refers to use one or more than one hormone medicines to suppress the over-reactive immune reaction read more
Patients are suggested to treat kidney disease first before they get pregnant read more
If you are diagnosed with Kidney Disease, you should talk to your doctor about starting an exercise read more
Foods and Drinks play an important role in Kidney Disease patients read more
Kidney Disease News and Events read more
In every week, a famous experienced renal medicine specialist will be invited to help diagnose and evaluate inpatient's disease condition, offering detailed therapeutic schedule. read more
Membranoproliferative glomerulonephritis (MPGN) is a disease that affects tiny blood vessels in kidneys.It can be attributable to a number of causes, such as autoimmune disorder,infection,hereditary disease etc. MPGN can be divided into three histologic types.What is MPGN type III prognosis?
MPGN type III is an immune complex disease with immune complexes in the subepithelial space.To eliminate these immune complexes from body, an inflammatory response is initiated in body.The abnormal immune system activity can cause progressive renal function decline.
If type III MPGN is associated with another condition or disease such as lupus, hepatitis, it usually can resolve if the associated condition or disease is controlled successfully.
If MPGN is idiopathic,it often has a worse prognosis.Approximately 50~60% of untreated patients will progress into end stage renal disease (ESRD) within 10~15 years, while 25-40% of untreated patients will continue to have normal renal function.Spontaneous remission or improvement occurs in less than 10% of cases.
The following factors can worsen the prognosis of type III MPGN significantly:
*Nephrotic Syndrome:a kidney disorder with heavy protein in urine
*High blood pressure: keeping blood pressure under 130/80mmHg can improve the prognosis
*Crescents on kidney biopsy
The above are the influencing factors of MPGN type III prognosis,but the treatment plays the key role.
Regular treatments of MPGN mainly include steroids and immunosuppressive drugs as well as some medicines to control symptoms. However, many patients still develop Kidney Failure with these treatments. To improve the prognosis of MPGN,immunotherapy is a recommended treatment. Firstly, it can suppress the abnormal immune system activity, thus blocking more immune damage to kidneys.Additionally,it can degrade the immune complexes in kidneys and make them out of body.Once the triggering factor of abnormal immune response is eliminated, the relapse of abnormal immune system activity will be inhibited completely.What’s more, it can stimulate the self-regeneration of impaired kidney tissues, thus improving renal function.
However, immunotherapy is not appropriate to all patients with MPGN. You can consult our medical profession to know if it is a right treatment choice for you.
What else you want to know:
How can I get this treatment?
How can I get this treatment in my countries?
How much does this treatment cost?
What is the duration if I receive this treatment in your hospital?
What should I prepare to your hospital except visa?
How can I go to your hospital?