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Tests to Confirm the Diagnosis of Henoch-Schonlein Purpura

Provided by Expert Zhang Youkang on 2013-01-07 14:27

An accurate diagnosis is the key for making an individualized treatment plan for Henoch-Schonlein purpura. The following tests can help confirm diagnosis of Henoch-Schonlein purpura.

Firstly, a physical exam and a medical history can help a lot in diagnosis of the condition. The patients often develop classic rash, joint pain and gastrointestinal symptoms.

Blood test

If Henoch-Schonlein purpura occurs, a special type of protein called IgA will elevate, but it is not conclusive. Additionally, test for measuring sed rate is suggested. Elevated sed rate indicate the level of inflammation in the body.

Urine tests

Kidney damage is the most serious complication of Henoch-Schonlein purpura. It can occur several months later after the onset of purpura. Urine tests can used to evaluate how your kidneys are functioning. Blood and proteins in urine can indicate kidney damage and the extent to which the kidneys are affected by the disease.

Skin biopsy

When skin biopsy is performed, a small sample of skin is examined under a microscope. If Henoch-Schonlein purpura occurs, the presence of IgA can be seen in blood vessels.

Renal biopsy

Renal biopsy is a medical procedure in which a small piece of kidney is removed from the body for examination. It is an invasive procedure. Usually, it is suggested if the patients show serious symptoms of kidney damage. Renal biopsy can tell the pathological type of Henoch-Schonlein purpura and the kidney damage degree. It can help the patients to make a personalized treatment plan for the patients.

The above are tests can give you an accurate diagnosis of Henoch-Schonlein purpura nephritis. After the diagnosis is confirmed, you should seek for treatment immediately to prevent more serious outcomes.

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