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Henoch-Schonlein Purpura (HSP) is a form of blood vessel inflammation or vasculitis. There are many different conditions that feature vasculitis. Each of the forms of vasculitis tends to involve certain characteristic blood vessels. HSP affects the small vessels called capillaries in the skin and frequently the kidneys. HSP results in a purplish skin rash (most prominent over the buttocks and behind the lower extremities) associated with joint inflammation (arthritis) and sometimes cramping pain in the abdomen. Henoch-Schonlein purpura is also referred to as anaphylactoid purpura. So what should be pay attention to for Purpura Nephritis patients?If you have any question please ask our ONLINE DOCTOR directly for free.
While HSP is generally a mild illness that resolves spontaneously, it can cause serious problems in the kidneys and bowels. The rash can be very prominent, especially on the lower extremities.
The treatment of HSP is directed toward the most significant area of involvement. Joint pain can be relieved by anti-inflammatory medications such as aspirin or ibuprofen (Motrin). Some patients can require cortisone medications, such as prednisone or prednisolone, especially those with significant abdominal pain or kidney disease. With more severe kidney disease, involvement called glomerulonephritis or nephritis, cyclophosphamide (Cytoxan), azathioprine (Imuran), or mycophenolate mofetil (Cellcept) have been used to suppress the immune system. Infection, if present, can require antibiotics.
Patients should be pay attention to the balance between water and electrolyte. When patients have the symptoms of edema and heavy proteinuria then they should be taken less salt, limited water and avoid taking high protein food. To prevent recurrence of purpura and worsen kidney damage, patients should pay attention to prevent the upper respiratory tract infection, removal of chronic infection lesion such as chronic tonsillitis, pharyngitis, searching for possible allergen positively, and avoiding contact again.
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