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Purpura Nephritis is an immunological disorder caused by allergic purpura. It is commonly seen in children and adults mainly featured with blood and proteins in urine. When purpura occurs, many people worry they will develop kidney disease. Will all people with allergic purpura will suffer from kidney damage?
In allergic purpura, the most of renal capillaries will be involved. However, in clinic, only 20~60% patients present with glomerular damage. When kidneys are involved, it will result in the following signs and symptoms.
1. Hematuria and proteinuria can occur. In acute period, gross hematuria is present and then changes into microscopic hematuria afterwards. Meanwhile, cylindruria can also be seen.
2. Some patients with kidney damage due to allergic lupus show the clinical manifestations of acute nephritis. They can experience hematuria, proteinuria, swelling, high blood pressure, reduced urine output and even renal function decline. In some cases, it can progress into chronic nephritis.
3. Nephrotic syndrome can occur. It is a syndrome featured with heavy proteinuria(>3.5 g/24h), severe swelling, hypoproteinemia. This condition usually indicates a poor prognosis. In some cases, the renal function can keep declining progressively.
If the patients with purpura have the above symptoms, they are suspected to have kidney damage and should do further examination.
As kidney damage usually starts and develops latently in allergic purpura, it may not show noticeable symptoms in early stage. Therefore, if purpura occurs, the patients are recommended to go to see doctor and do monitoring regularly so as to find kidney damage in the first time.
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