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What Does Amyloidosis Do to Kidneys

Provided by Expert Zhang Youkang on 2013-07-09 14:59

Amyloidosis refers to collections of protein strands and they can be seen under the microscope.Amyloidosis itself is not harmful, but it may cause damage to body tissues and interfere with the normal function when it is laid down within body.Renal amyloidosis is one of serious manifestations of amyloidosis.

What does amyloidosis do to kidneys?

Amyloid can lodge in the blood vessels and the tiny filters in kidneys. The deposits can cause inflammation in kidneys, resulting in kidney problem. As the renal filters fail to work normally, a myriad of symptoms and condition will occur.

Protein in urine

In right condition, proteins are too large to pass through the filters.However, when the filters are impaired, a large amount of protein will leak into urine. If excess protein is lost in urine, the urine will become foamy.


The obvious sign of Renal Amyloidosis is ankle swelling. In some severe cases, the swelling may affect the legs up to thighs, with fluid around the hands and face. In serious, the lung can be flooded with fluid, resulting in shortness of breath.

Kidney Failure

As there is no a cure for renal amyloidosis, some treatments only can control the symptoms. As a result, progressive renal function decline can result in kidney failure. When kidney failure occurs, itching or tiredness and sickness can occur.

Treatment for renal amyloidosis

There are several types of treatment for renal amyloidosis,but these treatments mainly focus on controlling symptoms.

Blood clots

Blood clots can occur in amyloid. Anticoagulant drugs will be recommended to patients.

Protein loss

A low-protein diet is recommended to the patients. However, if inadequate protein is not included in diet, the patients may become weak. So you should consult a dietitian to get an tailored diet plan.


If antibody production is causing amyloid, some drugs may be prescribed to suppress bone marrow. However, it may cause some risks.

However,the above treatments only can control the symptoms of renal amyloidosis. Here you can learn more information on treatments for renal amyloidosis.

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