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Uric Acid Nephropathy Prognosis and Prevention

Provided by Expert Zhang Youkang on 2012-09-15 10:47

Prognosis of Uric Acid Nephropathy

Uric Acid Nephropathy leads to a poor prognosis. Many current treatments only focus on the symptoms and kidney damages. However, they fail to develop a therapy from the root cause—abnormal immune system. This leads to repeated occurrence after treatment, which is commonly responsible for final dialysis.

Prevention of Uric Acid Nephropathy

Uric Acid Nephropathy can be caused by many factors such as big meals that contain too much meats and alcohol. People can take many measures to prevent this disease. The most important point is to remove the factors that lead to hyperuricemia. When the dietary habits and lifestyle have been modified, the concentration of urate in the blood can be decreased, but some patients may still have to take medicines to control the hyperuricemia.

In order to prevent Uric Acid Nephropathy, people may need to take medicines for the rest of life to lower the serum urate concentration. If the concentration is reduced to less than 6.0mg/dl (360μmmol/L), the episode of gout can be prevented; if the level is decreased to less than 5.0mg/dl (300μmmol/L), the tophi can be absorbed. Besides, pay attention to the side effects of preventive treatment. Consult the doctor about corresponding solutions.

Controlling the blood uric acid is the most effective measure which can delay the progression of kidney disease. The following are detailed preventive methods:

·Adjust daily diet. Avoid eating too much meat, as meat contain much purine and make urine to become acidic. Control the intake of protein. Eat more fresh vegetables, fruits, as well as foods that are rich in vitamins.

·Drink much water. The daily urine output can be 2,000~3,000ml. Drink water before going to sleep in order to increase the night urine output. This contributes to the excretion of small calculi and infection control.

·Alkalize the urine. Keep the urine pH between 6.5~6.8.

·Medicine treatment. Take medicines to promote the uric acid excretion and uric acid synthesis inhibitors.

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