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Uric Acid Nephropathy

Uric acid basic

Uric Acid Nephropathy refers to a condition of kidney damage that occurs when there is excess uric acid in the body. With extreme high level of uric acid, crystals form in the tissues of the body. When this happens in the kidneys, it is called Uric Acid or Gouty Nephropathy.

The disease can be divided into two types: Acute Uric Acid Nephropathy and Chronic Uric Acid Nephropathy. As for the former one, it is usually associated with leukemia or lymphoma.

Pathogenesis of Uric Acid Nephropathy

Nearly all of people with hyperuricemia will experience kidney damage in different degrees, which refers to Uric Acid Nephropathy. This is a typical secondary nephropathy in which immune system fails to work normally. Immune system functions as the defenders of our health. However, in people with this kidney disease, immune system attacks native tissues, including joint and kidneys.

Uric acid comes from the breakdown of purines in the diet. It too much of uric acid is made, or one's body fails to efficiently clear away this substance, then this can lead to occurrence and build up of uric acid crystal in the blood. In this case, blood vessels are damaged easily. Because of the infection by infectious agent in blood, inflammation happens in the wound of cells in blood vessels. Immune complexes will be formed and cannot be clear away timely, resulting in settling on the renal tissues and cells. Next new round of inflammation starts for renal tissues cannot bear the deposition of immune complexes. Then inflammation will continue all the time and make a great damage for renal function.

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

People with hyperuricemia blood may not know it for they cannot feel sick, but the disease may develop into Uric Acid Nephropathy when they detect it. Have an early examination and receive prompt treatment if you have one or several of the symptoms of Uric Acid Nephropathy as below:

Uric acid symptoms

·Joints hot, red, swelling and marked pain (acute type of kidney disease)

·Nodules of the joints with repeated attacks of arthritis for years (chronic type of kidney disease)

·Decreased urine output

·Frequent urination at night

·High creatinine level

·High uric acid level, usually higher than 1

·Uric acid stone

·Swelling or edema

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Uric acid treatment

1. Conventional treatment

·The purpose of treatment is to stop the immediate problems and prevent them from coming back. Besides, prevent complications which come from longstanding gout or high uric acid in the tissues. This is often done with medications.

· If the start of Kidney Failure has been sudden and more severe, dialysis may be used.

·Take a special diet which is low in purines.

· Keep up a good fluid intake. Drink enough water to put out 2 to 3 quarts or liters of urine per day.

2. Systemic treatment for Uric Acid Nephropathy - Immunotherapy

The treatment is aimed at dealing with the symptoms, underlying immune disorder and kidney damages. You can expect from Immunotherapy:

● Alleviation of symptoms, including decreased blood in urine, cleanse of uric acid stone, released joint pain, etc.

● Improvement in immunity. Immunotherapy can regulate the immune system to work normally and stop the further damages to native tissues.

● Increased kidney functions. Immunotherapy can repair the damaged kidney tissues and recover the declined kidney functions through the applications of integrated Chinese and western medicines, such as Micro-Chinese Medicine Osmotherapy, Medicated bath, Mai Kang He Ji and so on.

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Uric acid test

Uric Acid Nephropathy is a medical condition in which immune disorder causes renal damaged. Thereby, to make an precise diagnosis of this disease, a series of lab tests need to be done.

1. Immune special examination

▪ Toxin in Blood Tests. Aims: 1) Make the buildup of toxins in the body clear; 2) guide the choice of immune clearance method.

Checking items include: BUN, Creatinine, UA, β 2-microglobulin, Cyc C, RBP, HCY, and PTH.

▪ Kidney Damage Tests. Aims: 1) confirm the kidney damage; 2) the damaged part, glomerulus or renal tubules; 3) make the severity of kidney damage clear and guide the clinical choice of medicine; 4) judge patient's sensitivity to medicines and guide the clinical medicine application.

Checking items include: UTP, U-malb, U-TRF, U-IGG, β 2-microglobulin, α1-microglobulin, α2-macroglobulin, κ light chain, λ light chain, U- NAG, U-GGT, and Uosm.

2. General special examination

·Series of blood fat test. Aims: 1) judge whether patent's blood fat level has become elevated or the degree of increasing; 2) types of hyperlipidemia; 3) guide the clinical clearance method of blood fat. It can be divided into 7 check items of blood fat (triglyceride, total cholesterol, HDL, LDL, Apo A1, Apo BT, lipoprotein a) and 9 check items of blood fat.

·9 check items of blood fat. Checking items include: BUN, Creatinine, UA, β 2-microglobulin, Cyc C, RBP, HCY, PTH, Apo E and free fatty acids.

Abnormally elevated serum Apo E level is the most featured index of lab test for lipoprotein glomerulopathy. Serum free fatty acids can reflect the human body fat metabolism and blood fat level. It is also an important substance that causes insulin resistance, which has significant meaning for clinical diagnosis of Diabetes and decrease risk factor of cardiovascular disease.

·Series of sugar metabolism test. Aim: index to judge the dysfunction of human body metabolism; produce index for clinical treatment and treatment effect, including blood sugar, HbA1c, insulin, and C-peptide.

Blood sugar reflect the level of glucose in the blood. HbA1c reflects the averaged level of blood sugar in recent three months. Insulin and C-peptide reflect human body's adjustive ability of sugar metabolism. Sugar metabolism dysfunction may accelerate the progression of kidney disease.

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Uric acid knowledge

Pregnancy and Uric Acid Nephropathy

Pain is a great problem for patients with uric acid nephropathy during pregnancy. Being a painful condition, managing the gout in pregnancy becomes imperative so as to ensure than expectant mother doesn't face unnecessary discomfort. Due to the fetus, doctors may not describe you any medicines to alleviate your pain. However, a lifestyle changes will be very helpful.

You need to make a special diet plan with the help of your dietitian. Drinking a lot of water is essential during pregnancy for it helps to dilute the uric acid levels and flush out impurities from the kidneys. Food rich in vitamin C helps in enhancing the functioning of the kidneys.

In addition, you are suggested to reduce the animal protein intake and avoid alcohol. Cutting down on protein may not be so easy and you need take some nourishment throughout your pregnancy.

Sexual Life and Uric Acid Nephropathy

Uric Acid Nephropathy doesn't affect every patient greatly. However, in some cases, Uric Acid Nephropathy has effects on the sexual function and sexual desire. High uric acid level itself, or hyperuricemia men's sexual function does not exist on adverse effects gout patients have normal sexual function and reproductive ability. But when the joint deformity occurs when the number of sex life will cause inconvenience, such as knee pain and swelling, the use of male and upper posture will have painful intercourse discomfort feeling.

In addition, some medicine may also interfere with the sexual desire or sexual functions.

Healthy lifestyle and mental management helps alleviate the symptoms of Uric Acid Nephropathy during pregnancy and sexual life.

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Uric acid health care

For individuals with Uric Acid Nephropathy, their uric acid levels are higher than normal range (3~7mg/dL). It is crucial to develop a healthy lifestyle and lower the uric acid levels. The easiest and healthiest method is to have a reasonable arrangement of daily diet.

·Improve the intake of dairy foods

Dairy foods, such as low fat milk, yogurt and cheese, help gouty nephropathy patients lower uric acid level and feel released.

·Involve fruits and vegetables into daily diet

Fruits and vegetables should be managed in the list of diet, because most fruits and vegetables benefit the gouty disease a lot, such as blueberries, cherries, kale, cabbage, tomatoes etc.

·Drink enough water

People who have no swelling or edema are recommended to drink enough water. Liquids that are low in caffeine and calories help to remove uric acid from the blood stream.

·Avoid alcohol

This helps lower uric acid level. Most alcohols (beer and wine) are rich purine which contains much acid.

·Keep a healthy weight

Lose weight if necessary. However, keep in mind that dropping a significant amount of weight in a short time may induce uric acid level.

If you have been diagnosed with Uric Acid Nephropathy, we're here to help. Call us: +86-311-86954186 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

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